Margaret Oakley Dayhoff, often hailed as the "mother and father of bioinformatics," laid the groundwork for sequence alignment by developing one of the first substitution matrices, known as point accepted mutations (PAM).

The Dayhoff Bioinformatics Cluster at AS-BCST provides a high-performance computational environment for the local research community. Supported by Academia Sinica and maintained by the Bioinformatics and Computational Genomics group, the Dayhoff cluster hosts over 650 CPU cores, 5.5 TB of RAM, and approximately 500 TB of storage for bioinformatics analysis. As a high-performance computing cluster with a focus on bioinformatics, Dayhoff comes pre-configured with common biological analysis software. A quick start guide is available for users.

For detailed information, please contact Mr. Te-Chang Hsu and Dr. Yao-Cheng Lin (ext 212).